Ligand-Based Stability Changes in Duplex DNA Measured with a Microscale Electrochemical Platform

Development of technologies for rapid screening of DNA secondary structure thermal stability and the effects on stability for binding of small molecule drugs is important to the drug discovery process. In this report, we describe the capabilities of an electrochemical, microdevice-based approach for...

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Détails bibliographiques
Auteurs principaux: Sarah M. Robinson, Zuliang Shen, Jon R. Askim, Christopher B. Montgomery, Herman O. Sintim, Steve Semancik
Format: Article
Langue:English
Publié: MDPI AG 2019-04-01
Collection:Biosensors
Sujets:
Accès en ligne:https://www.mdpi.com/2079-6374/9/2/54