The Use of Endo-Cellulase and Endo-Xylanase for the Extraction of Apple Pectins as Factors Modifying Their Anticancer Properties and Affecting Their Synergy with the Active Form of Irinotecan

The Use of Endo-Cellulase and Endo-Xylanase for the Extraction of Apple Pectins as Factors Modifying Their Anticancer Properties and Affecting Their Synergy with the Active Form of Irinotecan

Pectin constitutes an essential component of dietary fiber. Modified pectins from various sources possess potent anticancer and immunomodulatory activities. In this study, two pectins isolated from apple pomace by <i>Trichoderma</i> enzyme treatment, PX (with endo-xylanase) and PCX (with...

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Bibliographic Details
Main Authors: Jerzy Maksymowicz, Anna Palko-Łabuz, Beata Sobieszczańska, Mateusz Chmielarz, Mirosława Ferens-Sieczkowska, Magdalena Skonieczna, Agnieszka Wikiera, Olga Wesołowska, Kamila Środa-Pomianek
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceuticals
Subjects:
colon cancer
pectin
synergy
SN-38 (irinotecan)
apoptosis
inflammation
Online Access:https://www.mdpi.com/1424-8247/15/6/732

Internet

https://www.mdpi.com/1424-8247/15/6/732

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