Exosomes biogenesis was increased in metformin-treated human ovary cancer cells; possibly to mediate resistance

Abstract Background Exosomes derived from tumor cells contribute to the pathogenesis of cancers. Metformin, the most usually used drug for type 2 diabetes, has been frequently investigated for anticancer effects. Here, we examined whether metformin affects exosomes signaling in human ovary cancer ce...

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Bibliographic Details
Main Authors: Reza Abbasi, Vahid Nejati, Jafar Rezaie
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-024-03312-6