Insensitivity of paediatric HIV-1 subtype C viruses to broadly neutralising monoclonal antibodies raised against subtype B.

Insensitivity of paediatric HIV-1 subtype C viruses to broadly neutralising monoclonal antibodies raised against subtype B.

A Phase I clinical trial has been proposed that uses neutralising monoclonal antibodies (MAbs) as passive immunoprophylaxis to prevent mother-to-child transmission of HIV-1 in South Africa. To assess the suitability of such an approach, we determined the sensitivity of paediatric HIV-1 subtype C vir...

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Bibliographic Details
Main Authors: Elin Solomonovna Gray, Tammy Meyers, Glenda Gray, David Charles Montefiori, Lynn Morris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1502151?pdf=render

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http://europepmc.org/articles/PMC1502151?pdf=render

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