Brain–Barrier Regulation, Metal (Cu, Fe) Dyshomeostasis, and Neurodegenerative Disorders in Man and Animals

The neurodegenerative diseases (Alzheimers, Parkinsons, amyotrophic lateral sclerosis, Huntingtons) and the prion disorders, have in common a dysregulation of metalloprotein chemistry involving redox metals (Cu, Fe, Mn). The consequent oxidative stress is associated with protein plaques and neuronal...

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Bibliographic Details
Main Author: Susan Haywood
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Inorganics
Subjects:
Online Access:https://www.mdpi.com/2304-6740/7/9/108