17β-Estradiol-Induced Conformational Changes of Human Microsomal Triglyceride Transfer Protein: A Computational Molecular Modelling Study

Human microsomal triglyceride transfer protein (hMTP) plays an essential role in the assembly of apoB-containing lipoproteins, and has become an important drug target for the treatment of several disease states, such as abetalipoproteinemia, fat malabsorption and familial hypercholesterolemia. hMTP...

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Bibliographic Details
Main Authors: Yong-Xiao Yang, Peng Li, Pan Wang, Bao-Ting Zhu
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/7/1566