Efficacy of Quetiapine Monotherapy and Combination Therapy for Patients with Bipolar Depression with Mixed Features: A Randomized Controlled Pilot Study

Efficacy of Quetiapine Monotherapy and Combination Therapy for Patients with Bipolar Depression with Mixed Features: A Randomized Controlled Pilot Study

Effective pharmacotherapy of bipolar depression with mixed features defined by DSM-5 remains unclear in clinical treatment guidelines. Quetiapine (QTP) and valproate have potential treatment utility but are often inadequate as monotherapy. Meanwhile, the efficacy of combination therapies of QTP plus...

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Bibliographic Details
Main Authors: Zheng Wang, Danhua Zhang, Yanli Du, Yin Wang, Tingting Huang, Chee H. Ng, Huimin Huang, Yanmeng Pan, Jianbo Lai, Shaohua Hu
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceuticals
Subjects:
bipolar depression with mixed features
quetiapine
valproate
lithium
monotherapy
combination therapy
Online Access:https://www.mdpi.com/1424-8247/16/2/287

Internet

https://www.mdpi.com/1424-8247/16/2/287

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