Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes
GBPs are essential for immunity against intracellular pathogens, especially for Toxoplasma gondii control. Here, the molecular interactions of murine GBPs (mGBP1/2/3/5/6), homo- and hetero-multimerization properties of mGBP2 and its function in parasite killing were investigated by mutational, Multi...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/11479 |