Metformin protects against PM2.5-induced lung injury and cardiac dysfunction independent of AMP-activated protein kinase α2

Metformin protects against PM2.5-induced lung injury and cardiac dysfunction independent of AMP-activated protein kinase α2

Fine particulate matter (PM2.5) airborne pollution increases the risk of respiratory and cardiovascular diseases. Although metformin is a well-known antidiabetic drug, it also confers protection against a series of diseases through the activation of AMP-activated protein kinase (AMPK). However, whet...

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Bibliographic Details
Main Authors: Junling Gao, Juntao Yuan, Qiao'e Wang, Tong Lei, Xiyue Shen, Bingqing Cui, Fang Zhang, Wenjun Ding, Zhongbing Lu
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719309784

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http://www.sciencedirect.com/science/article/pii/S2213231719309784

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