Phosphorylation of drebrin by cyclin-dependent kinase 5 and its role in neuronal migration.

Phosphorylation of drebrin by cyclin-dependent kinase 5 and its role in neuronal migration.

Cyclin-dependent kinase 5 (Cdk5)-p35 is a proline-directed Ser/Thr kinase which plays a key role in neuronal migration, neurite outgrowth, and spine formation during brain development. Dynamic remodeling of cytoskeletons is required for all of these processes. Cdk5-p35 phosphorylates many cytoskelet...

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Bibliographic Details
Main Authors: Kazuya Tanabe, Hiroyuki Yamazaki, Yutaka Inaguma, Akiko Asada, Taeko Kimura, Junya Takahashi, Masato Taoka, Toshio Ohshima, Teiichi Furuichi, Toshiaki Isobe, Koh-ichi Nagata, Tomoaki Shirao, Shin-ichi Hisanaga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3956921?pdf=render

Internet

http://europepmc.org/articles/PMC3956921?pdf=render

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