The DNA/RNA helicase DHX9 contributes to the transcriptional program of the androgen receptor in prostate cancer

Abstract Background Prostate cancer (PC) is the most commonly diagnosed male malignancy and an important cause of mortality. Androgen deprivation therapy is the first line treatment but, unfortunately, a large part of patients evolves to a castration-resistant stage, for which no effective cure is c...

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Bibliographic Details
Main Authors: Lidia Chellini, Marco Pieraccioli, Claudio Sette, Maria Paola Paronetto
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:https://doi.org/10.1186/s13046-022-02384-4