Activation of endogenous retrovirus triggers microglial immuno-inflammation and contributes to negative emotional behaviors in mice with chronic stress

Activation of endogenous retrovirus triggers microglial immuno-inflammation and contributes to negative emotional behaviors in mice with chronic stress

Abstract Background The “missing” link of complex and multifaceted interplay among endogenous retroviruses (ERVs) transcription, chronic immuno-inflammation, and the development of psychiatric disorders is still far from being completely clarified. The present study was aimed to investigate the mech...

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Bibliographic Details
Main Authors: Han Bao, Jinqi Yan, Jiancheng Huang, Wenjuan Deng, Ce Zhang, Cong Liu, Ailing Huang, Qiao Zhang, Ying Xiong, Qiang Wang, Huanghui Wu, Lichao Hou
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Neuroinflammation
Subjects:
Endogenous retrovirus
Microglia
Immuno-inflammation
Cyclic GMP-AMP synthase
Stimulator of interferon genes
Chronic stress
Online Access:https://doi.org/10.1186/s12974-023-02724-x

Internet

https://doi.org/10.1186/s12974-023-02724-x

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