Dietary intervention reprograms bone marrow cellular signaling in obese mice

Dietary intervention reprograms bone marrow cellular signaling in obese mice

ObjectivesThe current study aimed to investigate the pathogenesis of obesity-induced impaired bone mass accrual and the impact of dietary intervention on bone density in the mouse model of obesity.MethodsMice were fed with chow diet (CD) for 10 months, high-fat-diet (HFD) for 10 months, or HFD for 6...

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Bibliographic Details
Main Authors: Yuxuan Zheng, Jiren Yan, Xiaofu Zhang, Hailong Cui, Zhenyuan Wei, Xiaoying Li, Qiuyu Wang, Biao Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Endocrinology
Subjects:
obesity
bone formation
bone mass accrual
diet intervention
Wnt signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1171781/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1171781/full

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