Further Characterization of Glycoform-Selective Prions of Variably Protease-Sensitive Prionopathy

Further Characterization of Glycoform-Selective Prions of Variably Protease-Sensitive Prionopathy

Prion is an infectious protein (PrP<sup>Sc</sup>) that is derived from a cellular glycoprotein (PrP<sup>C</sup>) through a conformational transition and associated with a group of prion diseases in animals and humans. Characterization of proteinase K (PK)-resistant PrP<sup...

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Bibliographic Details
Main Authors: Weiguanliu Zhang, Xiangzhu Xiao, Mingxuan Ding, Jue Yuan, Aaron Foutz, Mohammed Moudjou, Tetsuyuki Kitamoto, Jan P. M. Langeveld, Li Cui, Wen-Quan Zou
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pathogens
Subjects:
prions disease
Creutzfeldt-Jakob disease (CJD)
variably protease-sensitive prionopathy (VPSPr)
Gerstmann-Sträussler-Scheinker (GSS)
glycoform-selective prion formation
real-time quaking-induced conversion (RT-QuIC) assay
Online Access:https://www.mdpi.com/2076-0817/10/5/513

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https://www.mdpi.com/2076-0817/10/5/513

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