Characterization of gene regulatory networks underlying key properties in human hematopoietic stem cell ontogeny

Characterization of gene regulatory networks underlying key properties in human hematopoietic stem cell ontogeny

Abstract Human hematopoiesis starts at early yolk sac and undergoes site- and stage-specific changes over development. The intrinsic mechanism underlying property changes in hematopoiesis ontogeny remains poorly understood. Here, we analyzed single-cell transcriptome of human primary hematopoietic s...

Full description

Bibliographic Details
Main Authors: Fei Li, Yanling Zhu, Tianyu Wang, Jun Tang, Yuhua Huang, Jiaming Gu, Yuchan Mai, Mingquan Wang, Zhishuai Zhang, Jiaying Ning, Baoqiang Kang, Junwei Wang, Tiancheng Zhou, Yazhou Cui, Guangjin Pan
Format: Article
Language:English
Published: SpringerOpen 2024-04-01
Series:Cell Regeneration
Subjects:
Hematopoietic stem cell
Transcription factors
Lineage potential
Gene regulatory networks
Human induced pluripotent stem cells
Hematopoietic differentiation
Online Access:https://doi.org/10.1186/s13619-024-00192-z

Internet

https://doi.org/10.1186/s13619-024-00192-z

Similar Items