The m6A reader HNRNPC is a key regulator in DSS-induced colitis by modulating macrophage phenotype

Summary: m6A regulators were demonstrated to modulate the functions of intestinal epithelial and immune cells in the ulcerative colitis. This study aimed to elucidate whether and how the m6A reader heterogeneous nuclear ribonucleoprotein C (HNRNPC) regulates macrophage function in the colitis. We ob...

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Bibliographic Details
Main Authors: Xiaohui Fang, Yu Zhang, Ziliang Ke, Yang Zhang, Yiken Lin, Yibo Huang, Jianhua Zhou, Huiting Su, Jun Xu, Yulan Liu
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225000720