Integrated network pharmacology and experimental analysis unveil multi-targeted effect of 18α- glycyrrhetinic acid against non-small cell lung cancer

Integrated network pharmacology and experimental analysis unveil multi-targeted effect of 18α- glycyrrhetinic acid against non-small cell lung cancer

Non-small cell lung cancer (NSCLC) is one of the most malignant types of cancer with soaring incidence rates worldwide, attributed to its heterogeneity and complex etiology. Evidently, alternative anti-cancer therapies comprising traditional medicines and natural products have gained attention for t...

Full description

Bibliographic Details
Main Authors: Rasha Irshad, Nafis Raj, Gamal A. Gabr, Nikhat Manzoor, Mohammad Husain
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
18α-Glycyrrhetinic acid
triterpenoid
NSCLC
network pharmacology
apoptosis
EGFR-PI3K/AKT pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1018974/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1018974/full

Similar Items