Integrated network pharmacology and experimental analysis unveil multi-targeted effect of 18α- glycyrrhetinic acid against non-small cell lung cancer

Integrated network pharmacology and experimental analysis unveil multi-targeted effect of 18α- glycyrrhetinic acid against non-small cell lung cancer

Non-small cell lung cancer (NSCLC) is one of the most malignant types of cancer with soaring incidence rates worldwide, attributed to its heterogeneity and complex etiology. Evidently, alternative anti-cancer therapies comprising traditional medicines and natural products have gained attention for t...

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Bibliographic Details
Main Authors:	Rasha Irshad, Nafis Raj, Gamal A. Gabr, Nikhat Manzoor, Mohammad Husain
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Series:	Frontiers in Pharmacology
Subjects:	18α-Glycyrrhetinic acid triterpenoid NSCLC network pharmacology apoptosis EGFR-PI3K/AKT pathway
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.1018974/full

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