Ras isoforms: signaling specificities in CD40 pathway
Abstract Background Ras are small cellular GTPases which regulate diverse cellular processes. It has three isoforms: H-Ras, K-Ras, and N-Ras. Owing to the N-terminus (1–165 residues) sequence homology these isoforms were thought to be functionally redundant. However, only K-Ras-deficient mice but no...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12964-019-0497-1 |