Ras isoforms: signaling specificities in CD40 pathway

Abstract Background Ras are small cellular GTPases which regulate diverse cellular processes. It has three isoforms: H-Ras, K-Ras, and N-Ras. Owing to the N-terminus (1–165 residues) sequence homology these isoforms were thought to be functionally redundant. However, only K-Ras-deficient mice but no...

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Bibliographic Details
Main Authors: Arathi Nair, Sushmita Chakraborty, Late Anirban Banerji, Ankita Srivastava, Charudutta Navare, Bhaskar Saha
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-019-0497-1