Sacsin Deletion Induces Aggregation of Glial Intermediate Filaments

Sacsin Deletion Induces Aggregation of Glial Intermediate Filaments

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disorder commonly diagnosed in infants and characterized by progressive cerebellar ataxia, spasticity, motor sensory neuropathy and axonal demyelination. ARSACS is caused by mutations in the SACS gene that lead...

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Bibliographic Details
Main Authors: Fernanda Murtinheira, Mafalda Migueis, Ricardo Letra-Vilela, Mickael Diallo, Andrea Quezada, Cláudia A. Valente, Abel Oliva, Carmen Rodriguez, Vanesa Martin, Federico Herrera
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
ARSACS
GFAP
nestin
vimentin
glioma
STAT3
Online Access:https://www.mdpi.com/2073-4409/11/2/299

Internet

https://www.mdpi.com/2073-4409/11/2/299

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