Exome sequencing to explore the possibility of predicting genetic susceptibility to the joint occurrence of polycystic ovary syndrome and Hashimoto’s thyroiditis

Exome sequencing to explore the possibility of predicting genetic susceptibility to the joint occurrence of polycystic ovary syndrome and Hashimoto’s thyroiditis

A large body of evidence indicates that women with polycystic ovary syndrome (PCOS) have a higher risk of developing Hashimoto’s thyroiditis (HT) than healthy individuals. Given the strong genetic impact on both diseases, common predisposing genetic factors are possibly involved but are not fully un...

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Bibliographic Details
Main Authors: Natalia Zeber-Lubecka, Katarzyna Suchta, Maria Kulecka, Anna Kluska, Magdalena Piątkowska, Michal J. Dabrowski, Katarzyna Jankowska, Monika Grymowicz, Roman Smolarczyk, Ewa E. Hennig
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
polycystic ovary syndrome
autoimmune thyroid disease
Hashimoto thyroiditis (HT)
whole-exome sequencing (WES)
prediction model
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1193293/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1193293/full

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