Integrated Genomic Analysis of Primary Prostate Tumor Foci and Corresponding Lymph Node Metastases Identifies Mutations and Pathways Associated with Metastasis

Integrated Genomic Analysis of Primary Prostate Tumor Foci and Corresponding Lymph Node Metastases Identifies Mutations and Pathways Associated with Metastasis

Prostate cancer is a highly heterogeneous disease and mortality is mainly due to metastases but the initial steps of metastasis have not been well characterized. We have performed integrative whole exome sequencing and transcriptome analysis of primary prostate tumor foci and corresponding lymph nod...

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Bibliographic Details
Main Authors: Carlos S. Moreno, Cynthia L. Winham, Mehrdad Alemozaffar, Emma R. Klein, Ismaheel O. Lawal, Olayinka A. Abiodun-Ojo, Dattatraya Patil, Benjamin G. Barwick, Yijian Huang, David M. Schuster, Martin G. Sanda, Adeboye O. Osunkoya
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cancers
Subjects:
cancer genomics
metastasis
prostate cancer
tumor heterogeneity
Online Access:https://www.mdpi.com/2072-6694/15/23/5671

Internet

https://www.mdpi.com/2072-6694/15/23/5671

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