Nox2 modification of LDL is essential for optimal apolipoprotein B-mediated control of agr type III Staphylococcus aureus quorum-sensing.

Nox2 modification of LDL is essential for optimal apolipoprotein B-mediated control of agr type III Staphylococcus aureus quorum-sensing.

Staphylococcus aureus contains an autoinducing quorum-sensing system encoded within the agr operon that coordinates expression of virulence genes required for invasive infection. Allelic variation within agr has generated four agr specific groups, agr I-IV, each of which secretes a distinct autoindu...

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Bibliographic Details
Main Authors: Pamela R Hall, Bradley O Elmore, Cynthia H Spang, Susan M Alexander, Brett C Manifold-Wheeler, Moriah J Castleman, Seth M Daly, M Michal Peterson, Erin K Sully, Jon K Femling, Michael Otto, Alexander R Horswill, Graham S Timmins, Hattie D Gresham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3573103?pdf=render

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http://europepmc.org/articles/PMC3573103?pdf=render

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