Chronic Voluntary Alcohol Consumption Alters Promoter Methylation and Expression of <i>Fgf-2</i> and <i>Fgfr1</i>

Chronic Voluntary Alcohol Consumption Alters Promoter Methylation and Expression of <i>Fgf-2</i> and <i>Fgfr1</i>

Alcohol abuse accounts for 3.3 million deaths annually, rendering it a global health issue. Recently, fibroblast growth factor 2 (FGF-2) and its target, fibroblast growth factor receptor 1 (FGFR1), were discovered to positively regulate alcohol-drinking behaviors in mice. We tested whether alcohol i...

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Bibliographic Details
Main Authors: Leonie Herburg, Mathias Rhein, Sabrina Kubinski, Ekaterini Kefalakes, Matar Levin Greenwald, Simona Gielman, Segev Barak, Helge Frieling, Claudia Grothe
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
FGF-2
FGFR1
alcohol
addiction
epigenetic alteration
mesolimbic system
Online Access:https://www.mdpi.com/1422-0067/24/4/3336

Internet

https://www.mdpi.com/1422-0067/24/4/3336

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