Entoferritin: An innovative iron source for human consumption
The high prevalence of iron deficiency in humans, alongside the lack of sustainable iron sources call for alternatives. Although understudied, edible insects are high in potentially bioavailable iron. Insect ferritin is thought to make insect-based iron bioavailable (entoferritin). This review exami...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-09-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464623003110 |
| _version_ | 1797688967468941312 |
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| author | Tomer First Vincenzo Fogliano Maryia Mishyna |
| author_facet | Tomer First Vincenzo Fogliano Maryia Mishyna |
| author_sort | Tomer First |
| collection | DOAJ |
| description | The high prevalence of iron deficiency in humans, alongside the lack of sustainable iron sources call for alternatives. Although understudied, edible insects are high in potentially bioavailable iron. Insect ferritin is thought to make insect-based iron bioavailable (entoferritin). This review examined the use of entoferritin as an iron supplement based on its properties and comparison to mammalian and plant ferritins. Entoferritin is a large, soluble, iron-affine transporting protein complex. These features enable mild entoferritin purification. These purifying methods may not affect other products due to the common structure of edible insect processing chains. The protein complex can accumulate an abundance of bioavailable iron and be absorbed through a human endocytosis mechanism. However, insect ferritin delivery systems into the human iron pool, bioavailability and safety have various possible limits and require further exploration. This paper suggests that entoferritin could help the valorization of edible insects and fight iron deficiency. |
| first_indexed | 2024-03-12T01:38:12Z |
| format | Article |
| id | doaj.art-6fdfe8da36ec4fa3a3a46ef3fb997cc2 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-03-12T01:38:12Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-6fdfe8da36ec4fa3a3a46ef3fb997cc22023-09-11T04:16:45ZengElsevierJournal of Functional Foods1756-46462023-09-01108105711Entoferritin: An innovative iron source for human consumptionTomer First0Vincenzo Fogliano1Maryia Mishyna2Wageningen University and Research, Food Quality and Design Group, Bornse Weilanden 9, 6708 WG Wageningen, the NetherlandsWageningen University and Research, Food Quality and Design Group, Bornse Weilanden 9, 6708 WG Wageningen, the NetherlandsCorresponding author.; Wageningen University and Research, Food Quality and Design Group, Bornse Weilanden 9, 6708 WG Wageningen, the NetherlandsThe high prevalence of iron deficiency in humans, alongside the lack of sustainable iron sources call for alternatives. Although understudied, edible insects are high in potentially bioavailable iron. Insect ferritin is thought to make insect-based iron bioavailable (entoferritin). This review examined the use of entoferritin as an iron supplement based on its properties and comparison to mammalian and plant ferritins. Entoferritin is a large, soluble, iron-affine transporting protein complex. These features enable mild entoferritin purification. These purifying methods may not affect other products due to the common structure of edible insect processing chains. The protein complex can accumulate an abundance of bioavailable iron and be absorbed through a human endocytosis mechanism. However, insect ferritin delivery systems into the human iron pool, bioavailability and safety have various possible limits and require further exploration. This paper suggests that entoferritin could help the valorization of edible insects and fight iron deficiency.http://www.sciencedirect.com/science/article/pii/S1756464623003110Insect ferritinEntoferritinEdible insectsIron deficiencyIron bioavailabilityNonheme-protein based iron |
| spellingShingle | Tomer First Vincenzo Fogliano Maryia Mishyna Entoferritin: An innovative iron source for human consumption Journal of Functional Foods Insect ferritin Entoferritin Edible insects Iron deficiency Iron bioavailability Nonheme-protein based iron |
| title | Entoferritin: An innovative iron source for human consumption |
| title_full | Entoferritin: An innovative iron source for human consumption |
| title_fullStr | Entoferritin: An innovative iron source for human consumption |
| title_full_unstemmed | Entoferritin: An innovative iron source for human consumption |
| title_short | Entoferritin: An innovative iron source for human consumption |
| title_sort | entoferritin an innovative iron source for human consumption |
| topic | Insect ferritin Entoferritin Edible insects Iron deficiency Iron bioavailability Nonheme-protein based iron |
| url | http://www.sciencedirect.com/science/article/pii/S1756464623003110 |
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