Two Tier Hox Collinearity Mediates Vertebrate Axial Patterning
A two tier mechanism mediates Hox collinearity. Besides the familiar collinear chromatin modification within each Hox cluster (nanocollinearity), there is also a macrocollinearity tier. Individual Hox clusters and individual cells are coordinated and synchronized to generate multiscale (macro and na...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2018-09-01
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Series: | Frontiers in Cell and Developmental Biology |
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Online Access: | https://www.frontiersin.org/article/10.3389/fcell.2018.00102/full |