Hippocampal vulnerability to hyperhomocysteinemia worsens pathological outcomes of mild traumatic brain injury in rats

Background Mild traumatic brain injury (mTBI) generally resolves within weeks. However, 15-30% of patients present persistent pathological and neurobehavioral sequelae that negatively affect their quality of life. Hyperhomocysteinemia (HHCY) is a neurotoxic condition derived from homocysteine accumu...

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Bibliographic Details
Main Authors: Flaubert Tchantchou, Ru-ching Hsia, Adam Puche, Gary Fiskum
Format: Article
Language:English
Published: SAGE Publishing 2023-02-01
Series:Journal of Central Nervous System Disease
Online Access:https://doi.org/10.1177/11795735231160025