Targeting macrophages: a novel treatment strategy in solid tumors

Targeting macrophages: a novel treatment strategy in solid tumors

Abstract In the tumor microenvironment (TME), tumor-associated macrophages (TAMs) are the most abundant immune cells, which act as a key regulator in tumorigenesis and progression. Increasing evidence have demonstrated that the TME alters the nature of macrophages to maintain dynamic tissue homeosta...

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Bibliographic Details
Main Authors: Mengmeng Liu, Lina Liu, Yongping Song, Wei Li, Linping Xu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Translational Medicine
Subjects:
Tumor-associated macrophages
Solid tumors
Immunotherapeutic strategies
CD47 mAb
CD47 based BsAb
CAR-M
Online Access:https://doi.org/10.1186/s12967-022-03813-w

Internet

https://doi.org/10.1186/s12967-022-03813-w

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