Shear stress control of vascular leaks and atheromas through Tie2 activation by VE‐PTP sequestration
Abstract Vascular endothelial protein tyrosine phosphatase (VE‐PTP) influences endothelial barrier function by regulating the activation of tyrosine kinase receptor Tie2. We determined whether this action is linked to the development of atherosclerosis by examining the influence of arterial shear st...
Main Authors: | Keisuke Shirakura, Peter Baluk, Astrid F Nottebaum, Ute Ipe, Kevin G Peters, Donald M McDonald, Dietmar Vestweber |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2023-04-01
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Series: | EMBO Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.15252/emmm.202216128 |
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