The impact of TLR2 and aging on the humoral immune response to Staphylococcus aureus bacteremia in mice

Abstract Aging alters immunoglobulin production, affecting the humoral immune response. Toll-like receptor 2 (TLR2) recognizes Staphylococcus aureus (S. aureus) which causes bacteremia with high mortality in the elderly. To understand how TLR2 and aging affect the humoral immune response in bacterem...

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Bibliographic Details
Main Authors: Priti Gupta, Zhicheng Hu, Pradeep Kumar Kopparapu, Meghshree Deshmukh, Tibor Sághy, Majd Mohammad, Tao Jin, Cecilia Engdahl
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35970-3