NXN suppresses metastasis of hepatocellular carcinoma by promoting degradation of Snail through binding to DUB3
Abstract The poor prognosis of hepatocellular carcinoma (HCC) could be attributed to its high metastasis rate. Here, we report the role of nucleoredoxin (NXN), a multifunctional redox-active protein, in HCC metastasis. The expression of NXN in HCC tissues was measured by immunohistochemistry. The ro...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-08-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-05135-7 |