NXN suppresses metastasis of hepatocellular carcinoma by promoting degradation of Snail through binding to DUB3

NXN suppresses metastasis of hepatocellular carcinoma by promoting degradation of Snail through binding to DUB3

Abstract The poor prognosis of hepatocellular carcinoma (HCC) could be attributed to its high metastasis rate. Here, we report the role of nucleoredoxin (NXN), a multifunctional redox-active protein, in HCC metastasis. The expression of NXN in HCC tissues was measured by immunohistochemistry. The ro...

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Bibliographic Details
Main Authors: Yuanping Zhang, Dinglan Zuo, Jiliang Qiu, Kai Li, Yi Niu, Yichuan Yuan, Yuxiong Qiu, Liang Qiao, Wei He, Chenwei Wang, Yunfei Yuan, Binkui Li
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05135-7

Internet

https://doi.org/10.1038/s41419-022-05135-7

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