Transferrin-Conjugated Melittin-Loaded L-Arginine-Coated Iron Oxide Nanoparticles for Mitigating Beta-Amyloid Pathology of the 5XFAD Mouse Brain

Transferrin-Conjugated Melittin-Loaded L-Arginine-Coated Iron Oxide Nanoparticles for Mitigating Beta-Amyloid Pathology of the 5XFAD Mouse Brain

Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative diseases and a major contributor to dementia. Although the cause of this condition has been identified long ago as aberrant aggregations of amyloid and tau proteins, effective therapies for it remain elusive. The complexities of...

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Bibliographic Details
Main Authors: Moonseok Choi, Junghwa Ryu, Huy Duc Vu, Dongsoo Kim, Young-Jin Youn, Min Hui Park, Phuong Tu Huynh, Gyu-Bin Hwang, Sung Won Youn, Yun Ha Jeong
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
nanoparticle
melittin
iron oxide
transferrin
amyloid plaque
Online Access:https://www.mdpi.com/1422-0067/24/19/14954

Internet

https://www.mdpi.com/1422-0067/24/19/14954

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