SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease

SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease

Abstract Lyme disease is a tick-borne disease caused by bacteria of the genus Borrelia. The host factors that modulate susceptibility for Lyme disease have remained mostly unknown. Using epidemiological and genetic data from FinnGen and Estonian Biobank, we identify two previously known variants and...

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Bibliographic Details
Main Authors: Satu Strausz, Erik Abner, Grace Blacker, Sarah Galloway, Paige Hansen, Qingying Feng, Brandon T. Lee, Samuel E. Jones, Hele Haapaniemi, Sten Raak, George Ronald Nahass, Erin Sanders, FinnGen, Estonian Genome Centre, Estonian Biobank Research Team, Pilleriin Soodla, Urmo Võsa, Tõnu Esko, Nasa Sinnott-Armstrong, Irving L. Weissman, Mark Daly, Tuomas Aivelo, Michal Caspi Tal, Hanna M. Ollila
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45983-9

Internet

https://doi.org/10.1038/s41467-024-45983-9

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