Genetic Silencing of Fatty Acid Desaturases Modulates α-Synuclein Toxicity and Neuronal Loss in Parkinson-Like Models of C. elegans

Genetic Silencing of Fatty Acid Desaturases Modulates α-Synuclein Toxicity and Neuronal Loss in Parkinson-Like Models of C. elegans

The molecular basis of Parkinson’s disease (PD) is currently unknown. There is increasing evidence that fat metabolism is at the crossroad of key molecular pathways associated with the pathophysiology of PD. Fatty acid desaturases catalyze synthesis of saturated fatty acids from monounsaturated fatt...

Detaylı Bibliyografya
Asıl Yazarlar:	Malabika Maulik, Swarup Mitra, Ajiel Mae Basmayor, Brianna Lu, Barbara E. Taylor, Abel Bult-Ito
Materyal Türü:	Makale
Dil:	English
Baskı/Yayın Bilgisi:	Frontiers Media S.A. 2019-08-01
Seri Bilgileri:	Frontiers in Aging Neuroscience
Konular:	C. elegans fat Parkinson’s disease Δ9 desaturase α-synuclein dopamine
Online Erişim:	https://www.frontiersin.org/article/10.3389/fnagi.2019.00207/full

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