Perturbation-based Markovian transmission model for probing allosteric dynamics of large macromolecular assembling: a study of GroEL-GroES.

Large macromolecular assemblies are often important for biological processes in cells. Allosteric communications between different parts of these molecular machines play critical roles in cellular signaling. Although studies of the topology and fluctuation dynamics of coarse-grained residue networks...

Полное описание

Библиографические подробности
Главные авторы: Hsiao-Mei Lu, Jie Liang
Формат: Статья
Язык:English
Опубликовано: Public Library of Science (PLoS) 2009-10-01
Серии:PLoS Computational Biology
Online-ссылка:http://europepmc.org/articles/PMC2741606?pdf=render