The role of immune checkpoints in cardiovascular disease

The role of immune checkpoints in cardiovascular disease

Immune checkpoint inhibitors (ICI) are monoclonal antibodies which bind to immune checkpoints (IC) and their ligands to prevent inhibition of T-cell activation by tumor cells. Currently, multiple ICI are approved targeting Cytotoxic T-lymphocyte antigen 4 (CTLA-4), Programmed Death Protein 1 (PD-1)...

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Bibliographic Details
Main Authors: Laura I. Yousif, Anniek A. Tanja, Rudolf A. de Boer, Arco J. Teske, Wouter C. Meijers
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
immune checkpoint inhibitors
immune checkpoints
myocarditis
cardiomyopathy
atherosclerosis
PD-1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.989431/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.989431/full

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