A pharmacogenetic study of perampanel: association between rare variants of glutamate receptor genes and outcomes

A pharmacogenetic study of perampanel: association between rare variants of glutamate receptor genes and outcomes

Introduction: The selection of antiseizure medication usually requires a trial-and-error process. Our goal is to investigate whether genetic markers can predict the outcome of perampanel (PER) use in patients with epilepsy.Method: The studied participants were selected from our previous epilepsy gen...

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Bibliographic Details
Main Authors: Chih-Hsiang Lin, Chen-Jui Ho, Shih-Ying Chen, Yan-Ting Lu, Meng-Han Tsai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Genetics
Subjects:
perampanel
glutamate receptor gene
rare genetic variants
drug response
adverse drug reaction
1-year retention
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1215493/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1215493/full

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