Impact of Chromosome 9 Numerical Imbalances in Oral Squamous Cell Carcinoma: A Pilot Grid-Based Centromere Analysis

Impact of Chromosome 9 Numerical Imbalances in Oral Squamous Cell Carcinoma: A Pilot Grid-Based Centromere Analysis

Oral squamous cell carcinoma (OSCC) is considered an aggressive malignancy, mainly due to its increased propensity to provide local and distant lymph node metastases. Gross chromosome instability (CI; polysomy/aneuploidy/monosomy), combined or not with specific gene alterations, is implicated in the...

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Bibliographic Details
Main Authors: Efthymios Kyrodimos, Aristeidis Chrysovergis, Nicholas Mastronikolis, Evangelos Tsiambas, Christos Riziotis, Dimitrios Roukas, Panagiotis Fotiades, Chara Stavraka, Vasileios Ragos, Minas Paschopoulos, Vasileios Papanikolaou
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Diagnostics
Subjects:
carcinoma
oral
chromosome
polysomy
grid
microscopy
Online Access:https://www.mdpi.com/2075-4418/10/7/501

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https://www.mdpi.com/2075-4418/10/7/501

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