L-<i>myc</i> Gene Expression in Canine Fetal Fibroblasts Promotes Self-Renewal Capacity but Not Tumor Formation

Canines are useful in mammalian preclinical studies because they are larger than rodents and share many diseases with humans. Canine fetal fibroblast cells (CFFs) are an easily accessible source of somatic cells. However, they are easily driven to senescence and become unusable with continuous in vi...

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Bibliographic Details
Main Authors: So Hee Kim, Bokyung Kim, Jung Hak Kim, Dong-Hoon Kim, Seung Hoon Lee, Dong-Seok Lee, Hong J. Lee
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/8/1980