Aldosterone Blockade Reduces Mortality without Changing Cardiac Remodeling in Spontaneously Hypertensive Rats

Aldosterone Blockade Reduces Mortality without Changing Cardiac Remodeling in Spontaneously Hypertensive Rats

Background: The role of aldosterone blockers during transition from long-term compensated hypertrophy to dilated failure is not completely understood. In this study we evaluated the effects of early administration of spironolactone on cardiac remodeling, myocardial function, and mortality in spontan...

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Bibliographic Details
Main Authors: Marcelo D.M. Cezar, Ricardo L. Damatto, Paula F. Martinez, Aline R.R. Lima, Dijon H.S. Campos, Camila M. Rosa, Daniele M. Guizoni, Camila Bonomo, Antonio C. Cicogna, Rodrigo Gimenes, Luana U. Pagan, Marina P. Okoshi, Katashi Okoshi
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Papillary muscle
Spironolactone
Ventricular function
Heart failure
Myocardial function
Echocardiogram
Online Access:http://www.karger.com/Article/FullText/354526

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http://www.karger.com/Article/FullText/354526

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