Enhancement of the immunogenicity of influenza A virus by the inhibition of immunosuppressive function of NS1 protein

The truncation of the nonstructural NS1 protein is a novel approach for the generation of immunogenic attenuated influenza viruses. However, the innate immune mechanisms that cause the increased immunogenicity of influenza viruses with altered NS1 proteins are poorly understood. The goal of this stu...

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Bibliographic Details
Main Authors: Kirill A. Vasilyev, Maria A. Yukhneva, Anna-Polina S. Shurygina, Marina A. Stukova, Andrej Y. Egorov
Format: Article
Language:English
Published: Doctrine 2018-10-01
Series:Microbiology Independent Research Journal
Online Access:https://www.scienceopen.com/hosted-document?doi=10.18527/2500-2236-2018-5-1-48-58