The antioxidant and anti-inflammatory activities of avasopasem manganese in age-associated, cisplatin-induced renal injury

The antioxidant and anti-inflammatory activities of avasopasem manganese in age-associated, cisplatin-induced renal injury

Purpose: Cisplatin contributes to acute kidney injury (AKI) and chronic kidney disease (CKD) that occurs with greater frequency and severity in older patients. Age-associated cisplatin sensitivity in human fibroblasts involves increased mitochondrial superoxide produced by older donor cells. Experim...

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Bibliographic Details
Main Authors: Kranti A. Mapuskar, Casey F. Pulliam, Ann Tomanek-Chalkley, Prerna Rastogi, Hsiang Wen, Sanjana Dayal, Benjamin R. Griffin, Diana Zepeda-Orozco, Amy L. Sindler, Carryn M. Anderson, Robert Beardsley, Eugene P. Kennedy, Douglas R. Spitz, Bryan G. Allen
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Redox Biology
Subjects:
Acute kidney injury (AKI)
Chronic kidney disease (CKD)
Cisplatin
Superoxide dismutase mimetic
Avasopasem manganese
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723004238

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http://www.sciencedirect.com/science/article/pii/S2213231723004238

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