Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells

Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells

Abstract Duck Tembusu virus (DTMUV) is a neurotropic virus in the genus Flavivirus that causes massive economic losses to the poultry industry in China and neighbouring countries. Autophagy is pivotal in cellular responses to pathogens and in viral pathogenesis. However, little is known about the ro...

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Bibliographic Details
Main Authors: Qing Wang, Yaqian Jiang, Guangbin Bao, Weiping Yao, Qing Yang, Shuyue Chen, Guijun Wang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Veterinary Research
Subjects:
Duck Tembusu virus
incomplete autophagy
signalling pathways
viral replication
neuropathogenesis
Online Access:https://doi.org/10.1186/s13567-023-01235-0

Internet

https://doi.org/10.1186/s13567-023-01235-0

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