Clinical impact of fluoroquinolone-resistant Escherichia coli in the fecal flora of hematological patients with neutropenia and levofloxacin prophylaxis.

BACKGROUND: Fluoroquinolone prophylaxis in patients with neutropenia and hematological malignancies is said to be effective on febrile netropenia (FN)-related infection and mortality; however, the emergence of antibiotic resistance has become a concern. Ciprofloxacin and levofloxacin prophylaxis are...

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Bibliographic Details
Main Authors: Yong Chong, Shinji Shimoda, Hiroko Yakushiji, Yoshikiyo Ito, Takatoshi Aoki, Toshihiro Miyamoto, Tomohiko Kamimura, Nobuyuki Shimono, Koichi Akashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3898953?pdf=render