Comparison of two-dimensional and three-dimensional culture systems and their responses to chemotherapy in cells representing disease progression of high-grade serous ovarian cancer

High-grade serous cancer is the most common type of ovarian cancer and is usually diagnosed at advanced stages with high mortality due to recurrence and eventual resistance to standard platinum therapy. The aim of this study was to compare two-dimensional (2D) versus tridimensional (3D) cell culture...

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Bibliographic Details
Main Authors: Naya El Mokbel, Alicia A. Goyeneche, Rewati Prakash, Benjamin N. Forgie, Farah H. Abdalbari, Xing Zeng, Basile Tessier-Cloutier, Shuk On Annie Leung, Carlos M. Telleria
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580824002024