Multicentre, double-blind, randomised controlled clinical trial comparing intermittent cefoxitin administration versus loading bolus followed by continuous infusion for the prevention of surgical site infection in colorectal surgery: the PROPHYLOXITIN study protocol

Multicentre, double-blind, randomised controlled clinical trial comparing intermittent cefoxitin administration versus loading bolus followed by continuous infusion for the prevention of surgical site infection in colorectal surgery: the PROPHYLOXITIN study protocol

Introduction Surgical site infections (SSIs) are the second leading cause of healthcare-associated infections in Europe with the highest rates being reported in colorectal surgery (ranging from 9% to 30%). Surgical antibiotic prophylaxis (SAP) is one of the most efficient measures for SSI prevention...

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Main Authors: Denis Frasca, Marc Garnier, Sigismond Lasocki, Matthieu Boisson, Marion Faucher, Matthias Garot, Raphaël Cinotti, Stéphanie Chevalier, Sylvain Lecoeur, Christophe Aveline, Yohann Foucher, Quentin Saint-Genis, Julien Birckener, Vincent Gourdou, Claire Nicolle, Victor Schwindenhammer, Cécile Hannezo, Benjamin Puisney, Jean-Sébastien Aubert, Maxime Wodey, Charles Jean Lagarrigue, Anne Li
Format: Article
Language:English
Published: BMJ Publishing Group 2025-01-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/1/e088306.full

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https://bmjopen.bmj.com/content/15/1/e088306.full

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