Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy

Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy

Abstract Background Muscle atrophy is a common pathology associated with disuse, such as prolonged bed rest or spaceflight, and is associated with detrimental health outcomes. There is emerging evidence that disuse atrophy may differentially affect males and females. Cellular mechanisms contributing...

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Bibliographic Details
Main Authors: Megan E. Rosa‐Caldwell, Seongkyun Lim, Wesley A. Haynie, Jacob L. Brown, John William Deaver, Francielly Morena Da Silva, Lisa T. Jansen, David E. Lee, Michael P. Wiggs, Tyrone A. Washington, Nicholas P. Greene
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Protein catabolism
Males
Females
Muscle loss
Protein anabolism
Sex differences
Online Access:https://doi.org/10.1002/jcsm.12693

Internet

https://doi.org/10.1002/jcsm.12693

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