Polyols Permeability on Caco-2 Cells and Their Effects on Transport of Low-Permeability Drugs

Polyols Permeability on Caco-2 Cells and Their Effects on Transport of Low-Permeability Drugs

Some pharmaceutical excipients are able to modify intestinal permeability, thus influencing drug absorption and bioavailability. The effect of four polyols (mannitol, maltitol, sorbitol and xylitol) on the permeability of seven active pharmaceutical ingredients (API), representing different BCS clas...

Full description

Bibliographic Details
Main Authors: Damien Truffin, Olaf Häusler, Maryse Martin, Sandrine Cotier, Jerôme Laparre, Manilduth Ramnath
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Future Pharmacology
Subjects:
polyols
xylitol
sorbitol
maltitol
mannitol
BCS
Online Access:https://www.mdpi.com/2673-9879/3/1/16

Internet

https://www.mdpi.com/2673-9879/3/1/16

Similar Items