Metabolic Deficits in the Retina of a Familial Dysautonomia Mouse Model

Metabolic Deficits in the Retina of a Familial Dysautonomia Mouse Model

Neurodegenerative retinal diseases such as glaucoma, diabetic retinopathy, Leber’s hereditary optic neuropathy (LHON), and dominant optic atrophy (DOA) are marked by progressive death of retinal ganglion cells (RGC). This decline is promoted by structural and functional mitochondrial deficits, inclu...

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מידע ביבליוגרפי
Main Authors: Stephanann M. Costello, Anastasia Schultz, Donald Smith, Danielle Horan, Martha Chaverra, Brian Tripet, Lynn George, Brian Bothner, Frances Lefcort, Valérie Copié
פורמט: Article
שפה:English
יצא לאור: MDPI AG 2024-07-01
סדרה:Metabolites
נושאים:
conditional knockout (CKO) FD mouse model
eye health
familial dysautonomia (FD)
metabolomics
nuclear magnetic resonance
mass spectrometry
גישה מקוונת:https://www.mdpi.com/2218-1989/14/8/423

אינטרנט

https://www.mdpi.com/2218-1989/14/8/423

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