Metabolic Deficits in the Retina of a Familial Dysautonomia Mouse Model

Metabolic Deficits in the Retina of a Familial Dysautonomia Mouse Model

Neurodegenerative retinal diseases such as glaucoma, diabetic retinopathy, Leber’s hereditary optic neuropathy (LHON), and dominant optic atrophy (DOA) are marked by progressive death of retinal ganglion cells (RGC). This decline is promoted by structural and functional mitochondrial deficits, inclu...

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Bibliographic Details
Main Authors: Stephanann M. Costello, Anastasia Schultz, Donald Smith, Danielle Horan, Martha Chaverra, Brian Tripet, Lynn George, Brian Bothner, Frances Lefcort, Valérie Copié
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Metabolites
Subjects:
conditional knockout (CKO) FD mouse model
eye health
familial dysautonomia (FD)
metabolomics
nuclear magnetic resonance
mass spectrometry
Online Access:https://www.mdpi.com/2218-1989/14/8/423

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https://www.mdpi.com/2218-1989/14/8/423

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